CAUSES OF CHRONIC SINUSITIS

It can be difficult to determine the cause of chronic sinusitis. Some investigators think it is an infectious disease but others are not certain. It is an inflammatory disease that often occurs in patients with asthma. If you have asthma, an allergic disease, you may have chronic sinusitis with exacerbations. If you are allergic to airborne allergens, such as dust, mold, and pollen, which trigger allergic rhinitis, you may develop chronic sinusitis. An immune response to antigens in fungi may be responsible for at least some cases of chronic sinusitis. In addition, people who are allergic to fungi can develop a condition called "allergic fungal sinusitis." If you are subject to getting chronic sinusitis, damp weather, especially in northern temperate climates, or pollutants in the air and in buildings also can affect you.

If you have an immune deficiency disease or an abnormality in the way mucus moves through and from your respiratory system (e.g., primary immune deficiency, HIV infection, and cystic fibrosis) you might develop chronic sinusitis with frequent flare-ups of acute sinusitis due to infections. In otherwise normal individuals, sinusitis may or may not be infectious. In addition, if you have severe asthma, nasal polyps (small growths in the nose), or a severe asthma attacks caused by aspirin and aspirin-like medicines such as ibuprofen, you might have chronic sinusitis

The latest definition of sinusitis is as follows:

Chronic rhinosinusitis is now defined as a multi-factorial group of disorders characterized by inflammation involving

•  (1) the mucous membranes of the nasal cavity and paranasal sinuses,

•  (2) the fluids contained within these spaces, and

•  (3) possibly the underlying bone.

•  s / s of at least 12 weeks' duration

•  in association with persistent changes on the CT scan four weeks after medical treatment without intervening acute infection.